Weight loss from Eli Lilly’s Zepbound reversed slowly after treatment stopped

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Key Points

People who stopped taking Eli Lilly & Co.s Zepbound after about eight months regained half the weight theyd lost a year later, yet were significantly thinner than when they had started the obesity drug, according to a study..

Taking Zepbound for 36 weeks resulted in a 20.9% loss of body weight, according to the study published Monday in the Journal of the American Medical Association..

But after 88 weeks, a group no longer taking the drug after the first 8 months had still lost 9.9% of their weight..

Earlier studies have shown that people who stop taking popular obesity drugs from Lilly and Novo Nordisk A/S called GLP-1s are prone to regaining weight..

Still, the results indicate that some benefits are retained a full year later, said Louis Aronne, an obesity expert at Weill Cornell Medicine and lead study author..

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