Scientists decode abnormal build-up of proteins in neurons that cause Alzheimer’s

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Key Points

A team of Japanese researchers has identified how proteins collect abnormally in neurons which is a feature of neurodegenerative diseases like Alzheimers...

Diseases such as Alzheimers and Amyotrophic Lateral Sclerosis (ALS) are known to be accompanied by an abnormal build-up of proteins in neurons...

However, the trigger behind this accumulation remains unknown, according to the study that appeared in the journal eLife...

The team, led by Associate Professor Kanae Ando of Tokyo Metropolitan University, focused on the presence of mitochondria in axons, the long tendril-like appendages that stretch out of neurons and form the necessary connections that allow signals to be transmitted inside our brains...

As populations age and the prevalence of neurodegenerative conditions continues to increase, the teams findings present a vital step in developing therapies to combat these serious illnesses, the study noted..

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