Adherence to weight-loss drugs is far higher with Wegovy than older medicines

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Key Points

Wegovy to treat obesity in 2021 or 2022 were still taking it a year later, more than three times the rate of adherence with older medicines, according to an analysis of medical records and insurance claims data...

Only 13% of patients who started taking Contrave from Orexigen Therapeutics and 10% of those who started on Qsymia from Vivus between 2015 and 2022 were still filling their prescriptions a year later, researchers reported on Wednesday in the journal Obesity...

A July data analysis by pharmacy benefits manager Prime Therapeutics of 4,255 people with commercial health plans who had been prescribed GLP-1 drugs in 2021 found that only about a third were still taking it a year later...

Wegovy carries a list price of $1,349 per-package, while Eli Lilly's newer rival drug Zepbound is listed at $1,059.87 a month, although most patients will pay far less, especially if they have commercial insurance that covers the treatments...

"The high costs of novel anti-obesity medications and non-persistence with (these drugs) are increasingly becoming a concern and could inform decisions regarding coverage by third-party payers," said study leader Dr..

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