Key Points
A bone marrow transplant, in which healthy donor stem cells replace a patients unhealthy marrow, was her best chance at survival...
(The exact number of donors in the bank is proprietary, he says.) Ossiums frozen bone marrow has now been given to three people in total, including the Michigan woman, with a fourth transplant scheduled soon...
Negrin sees potential for deceased donor bone marrow transplants to help organ transplant patients, who currently must take immunosuppressive drugs for the rest of their lives to avoid their immune system attacking the new organ..
But because immune cells originate in the bone marrow, if they could receive a marrow transplant from the same donor, Negrin says patients couldin theorygo off immunosuppressive drugs...
However, theres some evidence that the freezing process can decrease the quality of stem cells and may slightly increase the risk of cancer relapse, so Devine says Ossiums approach may be more suitable for other types of patients, such as those with sickle cell disease, for whom bone marrow transplants can be a cure..
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