JNU scientists develop new vaccine candidate to battle malaria

Posted on:
Key Points

A team of scientists from Jawaharlal Nehru University (JNU) has identified a promising vaccine candidate that could pave the way for more effective prevention and treatment strategies against malaria...

Their research, published in the iScience journal by Cell Press, proposes the parasite's Prohibitin protein as a novel target for vaccine development...

The parasite's ability to develop resistance against anti-malarial drugs, coupled with the absence of an efficacious vaccine, has hindered progress in combating this deadly epidemic.. . Over hundreds of years, this deadliest parasite is responsible for taking millions of lives..

The research, led by Prof. Shailja Singh and Prof. Anand Ranganathan at the Special Centre for Molecular Medicine, JNU, has identified a novel host-parasite interacting complex that could be the key to unlocking a successful vaccine strategy.. "In our study, we have identified a novel PHB2-Hsp70A1A receptor ligand pair that helps the parasite gain infection inside the human host..

Lipids are an essential component of the cell involved in various vital processes of life and the malaria parasite targets some of these lipid molecules for its growth and development...