Covid-19 antibodies decline quickly: Study explains why

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Recent research indicates that mRNA Covid-19 vaccines may not generate long-lasting immune protection...

Recent research suggests that protective antibodies from Covid-19 vaccines, specifically the mRNA type, tend to decline within a few months..

By analysing bone marrow samples, researchers discovered that while antibodies were present initially, the immune cells responsible for sustained antibody production over the long term, called long-lived plasma cells, were largely absent...

In contrast, the same participants showed more stable, long-lived immune responses to vaccines for other diseases, like tetanus and influenza, indicating that the Covid-19 vaccines might not encourage the maturation of immune cells into long-lived plasma cells...

"Our findings show that current mRNA Covid-19 vaccines fall short in generating long-lived plasma cells," she said, suggesting that further research on updated vaccines or delivery methods is essential to improve immunity duration...