Key Points
Tokyo [Japan], September 8 (ANI): Periodontal disease, which affects the gums and tissues around the teeth, is one of the most common dental disorders globally..
Periodontal disease, which is most commonly caused by the growth and deposition of bacterial biofilm around the teeth, can eventually lead to tooth loss if not treated properly...
Several decades of clinical research have proven that the periodontal pathogen Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) is closely related to the onset and worsening of rheumatoid arthritis (RA), a serious autoimmune disease that affects joints..
Our research findings provide new insights into the link between periodontal pathogenic bacteria and the exacerbation of arthritis through inflammasome activation, offering important information on the long-debated relationship between periodontal disease and systemic diseases, highlights Professor Toshihiko Suzuki, one of the lead authors of the study...
Moreover, the outcome of our work could contribute to the development of treatment strategies for not only arthritis but also other systemic diseases, such as Alzheimers disease, which is also related to periodontal pathogenic bacteria, he adds with eyes set on the future..
