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New Delhi: Foods such as cakes, chips, cookies, crackers, fried foods, mayonnaise, margarine and ultra-processed foodswhich are rich in advanced glycation end products (AGEs)are a leading cause behind India being the worlds diabetic capital, a first-of-its-kind clinical trial has found...
The government-funded trialconducted by researchers from various institutions including the Indian Council of Medical Research (ICMR) and Madras Diabetes Research Foundation (MDRF) in Chennaihas shown that consumption of AGE-rich foods leads to inflammation in the body, an underlying cause of diabetes...
By following a low-AGE dietwhich includes foods low in AGEs, such as fruits, vegetables, whole grains, and low-fat milkoverweight and obese individuals can reduce oxidative stress in their bodies, which refers to the imbalance of free radicals and antioxidants that results in inflammation and cell damage...
Such data, the study said, are valuable as Indians are more prone to insulin resistance (a condition in which cells in the muscles and liver do not respond to insulin, a hormone produced by the pancreas, as a result of which the cells cannot take up glucose), type 2 diabetes (high blood sugar levels as a result of insulin resistance) and cardiovascular diseases...
At the end of 12 weeks, the researchers found that the insulin oral disposition indexa measure of insulin sensitivity, and how well pancreatic beta cells, which produce insulin, functionwas significantly increased in the low-AGE diet group, compared to the high-AGE diet group...
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Samosa, pakoda, chips triggering India's diabetes epidemic
07, Oct, 24A first-of-its-kind study in India suggests that a low-AGE diet could significantly reduce diabetes risk, a pressing issue given the country's status as the diabetes capital of the world.