Key Points
Scientists on Friday revealed that a cholesterol regulator can become a surprising player in mental health research, helping treat depression and anxiety...
In a review, published in the journal Brain Medicine, researchers Dr Xiaoyu Song and Professor Jan-Ake Gustafsson from the University of Houston and Karolinska Institutet (Sweden) shed light on the therapeutic potential of liver X receptor beta (LXR) in treating depression and anxiety...
According to the findings, the receptors deficiency in female mice leads to anxiety-like behaviour and impaired behavioural responses...
Professor Gustafsson said the connection between the receptor, traditionally associated with metabolic functions, and complex psychiatric disorders like depression and anxiety, underscores the interconnectedness of biological systems...
While the findings are promising, the authors caution that additional basic research and clinical trials are necessary to determine whether novel drugs targeting the receptor can be effectively utilised in treating neurological and neuropsychiatric diseases..
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