Researchers give insights into possible cause of Alzheimers disease

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Researchers at Case Western Reserve University will investigate the possibility that specific brain proteins are involved in the onset of Alzheimer's disease...

Nearly 7 million Americans 65 and older have Alzheimer's disease, and the condition claims more lives than breast and prostate cancer combined..

Eph receptors are proteins initially investigated by Bing-Cheng Wang, a professor of pharmacology at Case Western Reserve's School of Medicine, for their role in brain development and cancer..

These proteins, according to Matthias Buck, a professor of physiology and biophysics at the School of Medicine, and his colleagues, may be involved in the BBB's disintegration, which is crucial for protecting the brain from damage during strokes and the early stages of Alzheimer's disease..

Working with Buck's lab, which is studying a part of the Eph receptor protein using advanced imaging and computational techniques, researchers from Texas Tech University and the University of Tennessee will study how this protein behaves in living cells..