Key Points
In a significant breakthrough to help patients battling both HIV and tuberculosis (TB), a study led by an Indian-origin scientist found a cancer therapy that can help control TB and not interfere with combined antiretroviral therapy (cART).. cART is a treatment that uses a combination of three or more drugs to treat HIV infection...
While many cases of TB can be controlled with months of antibiotics, the infection can return in people who are immunocompromised as a result of HIV..
This is an important hurdle that this host-directed therapy had to clear in order to help patients battling both HIV and TB, said Professor Smriti Mehra, from Texas Biomedical Research Institute (Texas Biomed)..
In the study, published in the peer-reviewed journal JCI Insight, the scientist and her team focussed on the protein, called IDO (short for Indoleamine-2,3-dioxygenase) -- a therapy currently used in cancer...
The results showed the IDO inhibitor does not interfere with cART and is safe for patients with HIV...
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