Key Points
According to a study published in the journal Nature this month, the new class of antibiotic Zosurabalpin, developed by Swiss pharma giant Roche has been found to kill drug-resistant strains of carbapenem-resistantAcinetobacter baumannii (CRAB), called a superbug because it is highly resistant to existing antibiotics...
Any new antibiotic class that has the ability to treat infections caused by multidrug-resistant (MDR) bacteria such as CRAB would be a significant breakthrough, said the spokesperson, adding that Zosurabalpin has many features that position it to be a medical breakthrough...
The misuse and overuse of antimicrobials in humans, animals and plants are the main drivers in the development of drug-resistant pathogens, the world health body says.. Indias National Action Plan on AMR says that the country has among the highest burdens of bacterial infections an estimated 410,000 children aged five years or less die from pneumonia in India annually, with pneumonia accounting for almost 25 percent of all child deaths...
The emergence of resistance is not only limited to the older and more frequently used classes of drugs but there has also been a rapid increase in resistance to the newer and more expensive drugs, like carbapenems, the plan says.. A researcher working on an AMR-related project with the National Centre for Disease Control under the Union health ministry said the discovery of a new class of antibiotic that promises to treat superbug-related infection is astounding, even though it might take a few years to show efficacy in human trials...
Once we have completed the currently ongoing phase 1 trials, we will evaluate this data and work with all our collaborating partners to determine the next appropriate step, the spokesperson said.. Researchers tested Zosurabalpin against more than 100 CRAB samples from patients, and found that it was able to kill all of these bacterial strains...
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